Searchable abstracts of presentations at key conferences in endocrinology

ea0073oc9.3 | Oral Communications 9: Endocrine-Related Cancer | ECE2021

Dysregulation of alternative splicing unveils new avenues for targeting pulmonary carcinoids

Blázquez-Encinas Ricardo , Teresa Caro María , García-Vioque Víctor , Pedraza-Arévalo Sergio , Alors-Pérez Emilia , Dulcínea Herrera-Martínez Aura , Sánchez-Sánchez Rafael , Serrano-Blanch Raquel , Foll Matthieu , Fernández-Cuesta Lynnette , D Gahete Manuel , M Luque Raúl , Ibáñez-Costa Alejandro , P Castaño Justo

IntroductionDysregulation of alternative splicing is emerging as a new hallmark of cancer. This dysregulation may originate from mutations and/or altered expression of specific components of the splicing machinery. Indeed, our group has shown that the expression profile of the splicing machinery is altered in several types of cancer, including endocrine-related cancers. However, to date, the status of alternative splicing and its putative dysregulation h...